ANDROGENETIC ALOPECIA (AGA) IN WOMEN

By Dr. Nektarios Logaras – Dermatologist/Venereologist

Androgenetic Alopecia (AGA) is a dermatological condition that is successfully treated with the right treatment.

It is estimated that 98 out of 100 men and 70 out of 100 women will experience it at some point in their lives. Its main characteristic is the decrease in the hair density all over the scalp. This is called diffuse alopecia and affects men, women, and adolescents. Without treatment, people with Androgenetic Alopecia experience significant negative effects on their quality of life and psychology.

In Athens South Dermatology Clinic, the Androgenetic Alopecia (AGA) is treated by the experienced and specialized Dermatologist Dr. Nektarios Logaras following individualized protocols, having the most modern medical equipment. So, there is no hair loss and hair implantation can be avoided by prevention.

The etiology of Androgenetic Alopecia is multifactorial and polygenic. Androgen metabolism and receptors play a particularly important role. The action of dihydrotestosterone (DHT) and enzymes (5a reductase – I and II), which play an important role in the onset of the disease, has also been confirmed.

Hair loss (or thinning) differs between men and women, as it has a different clinical picture and hair loss distribution patterns are different. Early diagnosis and initiation of properly parameterized, and individualized treatment, with laboratory testing, detection and treatment of diseases such as thyroid disease, prevent and limit the fast progression of Androgenetic Alopecia (AGA).

AGA is due to the effect of androgens on genetically predisposed hair follicles. The Caucasian race has the highest frequency compared to other races. The severity and frequency increase over the years. At the age of 70, 80% of men and 45% of women have AGA.

A large number of children suffer from Adolescent onset AGA (AO-AGA) that is a special subtype of early onset AGA that requires special attention. The mean age of Adolescent onset AGA (AO-AGA) is 14 years in boys and 15 years in girls.

Etiology of androgenetic alopecia in women – girls

The prevalence of androgenetic alopecia (AGA) increased with advancing age and affects both men and women. The heredity impact in women with AGA is 54%when they have first-degree relatives suffering from AGA.

Androgens are not the only causative agent. Only a small percentage of women with hyperandrogenemia (hyprandrogenism) suffer from AGA. In womens, hyperandrogenemia (hyperandrogenism), the distribution of hair loss (thinning) may take the form analogous to that of men. Women with signs of hyperandrogenemia (hyperandrogenism) have hair loss, menstrual irregularities, acne, seborrhea, obesity and infertility.

Hyperandrogenism does not always mean increased androgen levels in blood tests.

The hair thinning pattern in women with AGA is different from that of men.

The differences in clinical appearance obviously reflect the presence in women of lower androgen levels, lower levels of 5α-Reductase (3 – 3.5 times lower levels in the frontal region of women than men)and higher levels of aromatase (6 times higher levels in the frontal region and 4 times in the occipital region of women than men).

Also, menopause is a special condition for women. It is a condition of relative hyperandrogenism as the secretion of powerful natural antiandrogens (progesterone and estrogen) stops, while the secretion of proandrogens (D4 androstenedione and dehydroepiandrosterone sulfate) is maintained.

In addition to menopausal disorders in the cycle, polycystic ovary syndrome (PCOS) can adversely affect the normal hair growth cycle. Pregnancy and lactation also have a significant effect. The intake of birth control pills or corticosteroids can also worsen the hair loss.

The diseases of the thyroid or parathyroid gland, the chronic diseases such as iron-deficiency anemia or the unbalanced diet (lack of vitamins), diabetes and autoimmune diseases such as Systemic Lupus erythematodus (SLE), alopecia areata as well as skin disorders such as fungal infections can cause and worsen hair loss, on both men and women.

Other causes of hair loss are the following:

-Some hairstyles such as ponytail and braids with intense pulling can cause hair loss.
-Also, hairdressing care treatments such as perms, straighteners, hair dyes and the use of oxygen can worsen hair loss.
-Trichotillomania, also hair-pulling disorder, is a mental disorder that involves recurrent, irresistible urges to pull out hair from your scalp, eyebrows or other areas of your body, despite trying to stop.

Diagnosis And Treatment of Hair Loss

In Athens South Dermatology Clinic, diagnosis and treatment are always performed only by the experienced and specialized Dermatologist Dr. Nektarios Logaras (MD).

1. Step One
Digital Trichoscopy

The Digital Trichorizogram by the FotoFinder Trichoscale is useful to differentially diagnose other causes of hair loss and hair thinning as well as for assessing the development and to evaluate the treatment.

-It is painless in contrast to the traditional trichorizogram and without hair loss.
-It calculates the number, density and the phase of hair growth cycle (anagen, catagen and telogen).
-It provides an accurate custom PDF report as well as archiving and printing of the results.

2. Step Two
Laboratory Test
In women, men, and children for the exclusion or confirmation and treatment of hair loss related diseases.

In women with signs of hyperandrogenism, we recommend a laboratory test for polycystic ovary syndrome or late-onset congenital adrenal hyperplasia.

3. Step Three
Prescription

Parametered prescription according to clinical and laboratory findings.
Individualized prescription according to age, gender, comorbidity, ability to comply with treatment but also the evaluation of previous treatments.

Prescription of topical and oral, approved and effective drug combinations, such as Minoxidil, Finasteride, etc. for the prevention but also for the reversal of hair loss, the re-emergence of new hairs and the maintenance of the result for a lifetime.

​​4. Step Four
Autologous PRP Treatment with the Automatic Multiple Injection System HYCOOX injector

The pioneering, first and only in Greece, automatic system HYCOOX Multi Suction Auto Injector is the latest achievement of technology in the field of automatic multiple injection for the scalp.

In contrast to traditional techniques (Syringes, Pistols, Pens).

-It is completely painless
-It is accurate in the amount of plasma injected into the scalp area.
-There have no leaks.
-It is precise in the depth of the skin where the plasma should be injected.
-It enables a completely safe and fast Treatment

After double centrifugation, the precious plasma which contains proteins with Growth and Regenerative properties, with the necessary addition of special activators is injected into the scalp, achieving strengthening, utilizing the regenerative mechanisms of our own body, after restoring the function of the hair follicles having as a result the regrowth of new hairs but also the maintenance of the result for a lifetime.

Before & After

The Doctor’s experience

Dr. N. Logaras MD
Dermatologist – Venereologist
Laser Dermatologic Surgeon

Graduate of Nottingham and Birmingham Universities of England.

-Degree in Medicine, Bachelor of Medicine and Bachelor of Surgery, The University of Nottingham, UK.
-Degree in Medical Biochemistry, Bachelor of Science (Medical Biochemistry), University of Birmingham, UK

Postgraduate Training of the American Academy of Dermatology at the Miami Convention Center in Miami, USA, and at the International Center of Lutronic, using Laser Systems for Medical and Cosmetic Applications, in Seoul, South Korea.

CAREER AND PROFESSIONAL EXPERIENCE

 

-Dermatologist – Venereologist, Private Clinic – Athens South Dermatology & Laser Center, Alimos
-Dermatology – Venereology Specialty, Hospital of Dermatologic & Venereal Diseases “Andreas Syggros”
-Former Doctor, Royal Derby | Derby Teaching Hospitals NHS Foundation Trust, England
-Former Doctor, Taunton and Somerset Hospital NHS Trust-Musgrove Park, England
-Former Doctor, Worthing and Southlands Hospitals NHS Trust, England
-Former Doctor, Queen Alexandra Hospital, England
-Former Doctor, Portsmouth Hospital NHS Trust, England
-Former Doctor, Brighton and Sussex University Hospitals NHS Trust, England

Dr. N. Logaras is member of the following Medical Societies.

-Hellenic Society of Dermatologic Surgery, Aesthetic Dermatology and Laser, attending its congresses since 2010.
-American Academy of Dermatology.
-Hellenic Society of Dermatology & Venereology (HSDV)
-American Society for Laser Medicine and Surgery
-European Society for Cosmetic and Aesthetic Dermatology

19 years of medical experience

Phone No. for Appointment: +302109821431